A pay-to-witness-public-key-hash (P2WPKH), also known as native SegWit or Bech32 address, is a modern, more efficient address format. SegWit addresses are opt-in, so not every application supports them, but the majority do, and should, today. SegWit adoption can be tracked on here.
Benefits of SegWit addresses include more resistance to input errors (as they are case insensitive and use error-correcting codes), and lower transaction fees. The fee saving will depend on the type of transaction but for a common transfer of funds it can be 30-40%.
SegWit addresses start with
bc1q and are case insensitive.